2018 March Ph.D. Admissions (Final)

Friday seminar by Mr. Rohit Kumar


IDG Lab/ Friday/ May 24, 2019/ TYLCV suppress host plant defenses against whitefly
Category: Research
Posted by: bedineel

 

 

TYLCV suppress host plant defenses against whitefly

 

Plant-virus-vector mutualism

 

Rohit Kumar

Most plant viruses are vectored by insects and the interaction between plant-virus-vector have ecological and evolutionary implications. Insect vectors often perform better in virus infected plants and this kind of interaction or mutualism between plant virus and vector promotes spread of virus and has huge agronomical effects. Tomato yellow leaf curl virus (TYLCV) belongs to Begomovirus genera which is a prominent group of plant viruses. They are widespread in tropical and sub-tropical agro-ecosystems and are transmitted by whiteflies (Bemisia tabaci). Working with the whitefly, TYLCV and N. benthamiana, this work has deciphered the molecular mechanisms involved in suppression of plant defense system against vector by TYLCV. Two viral proteins namely C2 protein and βC1 protein are involved in suppression of plant defense system. Both proteins downregulated the transcripts levels of host genes related to terpene synthesis which consequently promoted the survival and reproduction of whitefly vectors in infected plants. These proteins suppress the activity of MYC2 which is a major regulator of terpene biosynthesis genes and this interaction maybe direct or indirect. Taken together, their results demonstrate that TYLCV C2 and βC1 protein manipulate host defense system independently and explains how sophisticated mutualism has evolved in the begomoviruses insect vector system and also, it might lead to new strategies to combat their spread.